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:: Volume 28, Number 2 (4-2016) ::
2016, 28(2): 78-85 Back to browse issues page
Assessment of the Relationship Between Stress and Oral Lichen Planus: A Review of Literature
Farzaneh Agha Hosseini , Mahdieh Sadat Moosavi, Maryam Sadat Sadrzadeh Afshar, Nafiseh Sheykh Bahaei
Professor, Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences,Department of Oral Medicine, Schoolof Dentistry, Tehran University of Medical Science, The academy of medical sciences, Tehran, Iran , Aghahose@sina.tums.ac.ir
Abstract:   (184 Views)

Assessment of the Relationship Between Stress and Oral Lichen Planus: A Review of Literature


F. Agha Hosseini 1, M.S Moosavi 2, M.S Sadrzadeh Afshar 2, N. Sheykhbahaei 3.
1 Professor, Dental Research Center, Dentistry Research Institute, Department of Oral Medicine, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran 2 Assistant Professor, Dental Research Center, Dentistry Research Institute, Department of Oral Medicine, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran 3 Assistant Professor, Department of Oral Medicine, School of Dentistry, Kashan University of Medical Sciences, Kashan, Iran

Abstract
Background and Aim: Oral lichen planus (OLP) is a chronic inflammatory lesion. Psychological stress occurs when someone senses that environmental demands exceed his/her adaptive capability. Stress, anxiety, and depression have frequently been mentioned as possible factors related to the development of OLP, although this association remains controversial. In most studies, a positive correlation was found between psychological stress and OLP, although some found no significant association. In this review, we assess the possible role of psychological stress in the etiopathogenesis of OLP.
Materials and Methods: The methodological approach of this study was to search major databases from 1985-2014, using "oral lichen planus"," stress", "anxiety", "depression" and "psychological disorder” as search terms.
Results: A total of 45 scientific papers and abstracts in English were reviewed, and 10 articles met the necessary requirements. Stress evaluation methods of these articles were questionnaire, genetic polymorphisms at DNA level, measurement of body substances like hormones, and effect of drug therapy of psychiatric disorders on OLP patients. In order to include a study, OLP in patients must have been proven by clinical and histopathological criteria. Exclusion criteria were not explicit stating the OLP diagnosis, an inadequate number of the test subject in experimental and control groups, discrepancy (inconsistency) in sex and age between the case and control groups, and unreliable method of stress measurements.
Conclusion: Higher levels of stress in patients with OLP were confirmed. Reducing psychological stress and well-being of patients is an important factor that should be considered in the treatment of OLP.
Key Words: Stress, Psychological, Lichen planus, Oral, Anxiety

Keywords: Stress, Psychological, Lichen planus, Oral, Anxiety
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Type of Study: Review | Subject: Oral Medicine
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Agha Hosseini F, Sadat Moosavi M, Sadat Sadrzadeh Afshar M, Sheykh Bahaei N. Assessment of the Relationship Between Stress and Oral Lichen Planus: A Review of Literature . The Journal of Islamic Dental Association of IRAN (JIDA) . 2016; 28 (2) :78-85
URL: http://jidai.ir/article-1-1860-en.html
Volume 28, Number 2 (4-2016) Back to browse issues page
Journal of Islamic Dental Association of Iran

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